Baltimore, MD — Edmond Scientific Company (ESC) researchers will present their latest findings to the scientific community, and shared experiences with their colleagues at the annual meeting of the Society of Toxicology (SOT) in Baltimore in March 2017.
Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology.
ESC supported research in neurodegenerative disorders and injury, and integrative physiology and behavior. ESC research reported on the effects of toxic exposure in adult and aged populations on seizure activity and neuronal loss, and related it to the loss of hippocampal interneurons and reduced inhibition which may lead to increased susceptibility to the development of seizures in an aged population. Other research related to researching better treatments against pharmaco-resistant seizures using combinations of drugs aimed at reversing the effects of maladaptive receptor trafficking.
Funded by the National Institutes of Health (NIH), the research was performed to reduce the extensive neuropathology and long-term performance deficits of uncontrolled seizures as a result of exposure to toxic Chemical Warfare Nerve Agents (CWNAs). However, the research also has direct relevance to other aged-related medical research areas that focus on neuronal loss and neurotoxicity due to natural and artificial causes.